少女金伯莉（A.J. Cook 饰）与好友驱车去郊外游玩，途中她预见一场严重的连环交通事故，而自己和朋友也将命丧其中。猛然惊醒的金伯莉将车横在路中央，阻挡了后面的车辆。然而车祸仍然发生，金伯莉侥幸逃过...
一项把人当动物对待的行为实验出了差错，一名大学生操纵了这项研究导致了致命的结果。。。
锡德尼•普雷斯科特（内芙•坎贝尔饰）的母亲去世一周年，这个本该平静的加州小镇变成了一片血海！两名学生被残忍地杀害，凶手是一位带着面具的恐怖片爱好者。警方将锡德尼的男友比尔•卢米斯（斯基特•乌尔里奇饰）...
拥有不堪回首过去的安藤满男（佐藤浩市饰）一早接到同事宫下（鹤见辰吾饰）的电话，得知医科大读书时的好友高山龙司（真田广之饰）意外死亡。安藤为高山的尸体进行解剖，排除了自杀和他杀的原因，发现好友死于心肌梗塞。在警方的安排下，他见到了高山的情人高野舞（中谷美纪饰），却听到了朋友因一卷录像带而丧命的说辞。安藤自然不会相信虚无缥缈的臆测，谁知几天后高山的前妻浅川玲子（松岛菜菜子饰）和年幼的儿子也在车祸中死亡，损毁的车中破碎的录像机引起安藤的怀疑。未过多久，浅川的上司吉野（松重丰饰）登门拜访，讲述了关于贞子和诅咒录像带的一切真相。安藤的命运由此发生改变……本片根据铃木光司的同名原作改编。
On the eve of his high school graduation, Will Kidman (Liboiron) finally looks up from his books to catch the eye of the girl he’s longed for the last four years the mysterious Eliana Wynter (Shaw). He’s always been the shy kid, flying under the radar, but when he discovers a dark secret from his past that he is heir to a powerful line of werewolves he finds he has a choice to make between succumbing to his primal nature, or turning against his own, and maintaining his humanity. In order to fight the destiny of his legacy, and save Eliana as well as himself he must battle not only his growing blood lust but an army of fearsome beasts bent on killing him, Eliana...and then, us all. 高中毕业前夕，基德曼终于与他早就向往的女孩埃利安娜温特相爱成为情侣。 与此同时他也发现了一个黑暗的秘密，他即将成为狼人。现在，为了命运和爱情，以及他们的生活，他必须与日益增长的嗜血欲望战斗…
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